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Talk Investigating the structure of molecules inside cells

Investigating the structure of molecules inside cells


International Lecture given by Professor Wolfgang Baumeister.

In the past, macromolecular structures have been characterized by methods requiring their isolation and purification. When taken out of their functional context, information about their interactions within the cellular environment is lost. However, it is the interaction between the many molecular species inhabiting cells which underlies cellular functions. Many of them exist only fleetingly or, when integrated in supramolecular complexes, these may be rooted so deeply in cells that they cannot be isolated without affecting their structural integrity. 

Professor Baumeister will discuss a method, cryo-electrontomography, that has the unique potential to study the ‘molecular sociology’ of cells, combining the best structural preservation with 3D high resolution imaging.

The lecture will be webcast live and the video recording will be available shortly after the event.

Attending the event

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Image credit: The molecular sociology of the Hela cell nuclear periphery as revealed by cryo-electron tomography. Mahamid J et al. 2016 Visualizing the molecular sociology at the HeLa cell nuclear periphery. Science 351, 969-972.

Event details

Thu 21 Jun 2018, 6:30pm

Live subtitling by Stagetext

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Venue details

Royal Society
6-9 Carlton House Terrace
The Arts Council
The Arts Council
The Arts Council