Every word counts

Talk Wiring up the brain: How axons navigate

Wiring up the brain: How axons navigate

Photo: K-M Leung

Key facts

Genre: Talk with live subtitling


Ferrier Prize Lecture 2017 given by Professor Christine Holt FMedSci FRS.

The brain is made up of billions of nerve cells (neurons) that are wired together by axons and dendrites. The precision of this wiring allows us to accurately sense, interpret and interact with the outside world, which is crucial for survival. Many neurons are positioned far away from the targets so they face the formidable task of sending out an axon that must navigate correctly over a long distance to find its targets. This key step in wiring the brain, called axon guidance, occurs early in embryonic development mostly before birth in humans.

In this lecture, Professor Holt will describe work on how the eye makes its long-distance connections with the brain. She will discuss general mechanisms of guidance and the discovery that RNA-based mechanisms inside axons help to establish and maintain neural circuitry. 

This Prize Lecture will be webcast live and the video recording of the event will be available shortly after the event.

Booking information
The event is free to attend and no registration is required. Doors open at 6pm and seats are allocation on a first come first served basis.

Photo credit
Growth cone showing polarised mRNA translation (red) nearest to signal gradient on right. Credit K-M Leung.

Event details

Tue 28 Mar 2017, 6:30pm

Live subtitling

Venue details

The Royal Society (Brain)
6-9 Carlton House Terrace
The Arts Council
The Arts Council
The Arts Council